|Other encyclopedia topics:||A-Ag Ah-Ap Aq-Az B-Bk Bl-Bz C-Cg Ch-Co Cp-Cz D-Di Dj-Dz E-Ep Eq-Ez F G H-Hf Hg-Hz I-In Io-Iz J K L-Ln Lo-Lz M-Mf Mg-Mz N O P-Pl Pm-Pz Q R S-Sh Si-Sp Sq-Sz T-Tn To-Tz U V W X Y Z 0-9|
|Contents of this page:|
Alternative Names Return to topBuerger's disease
Definition Return to top
Thromboangiitis obliterans is a rare disease in which blood vessels of the hands and feet become obstructed.
Causes Return to top
Thromboangiitis obliterans (Buerger's disease) is caused by vasculitis (inflammation of the blood vessels).
The blood vessels of the hands and feet are especially affected, becoming constricted or totally blocked. This reduces blood flow to the hand and foot tissues, resulting in pain and eventually damage.
Thromboangiitis obliterans affects about 6 of every 10,000 people. It almost always affects men ages 20 to 40 who have a history of smoking or chewing tobacco.
The condition may also be associated with a history of Raynaud's disease.
This disorder is very uncommon in children, but may occur in those with autoimmune diseases.
Symptoms Return to top
Note: Symptoms may worsen with exposure to cold or with emotional stress. Usually, two or more limbs are affected.
Exams and Tests Return to top
The hands or feet may show enlarged, red, tender blood vessels. The pulse in the affected hands or feet may be low or absent.
The following tests may show blockage of blood vessels in the affected hands or feet:
Blood tests for other causes of vasculitis and inflammation may be done. Rarely, in cases where the diagnosis is unclear, a biopsy of the blood vessel is done.
Treatment Return to top
There is no cure for thromboangiitis obliterans. The goal of treatment is to control symptoms.
To prevent amputation, the patient must stop using tobacco and should avoid cold temperatures and other conditions that reduce circulation to the hands and feet.
Applying warmth and exercising gently may help increase circulation.
Cutting the nerves to the area (surgical sympathectomy) may help control pain. Aspirin and vasodilators may also used. Amputation of the extremity may be necessary if infection or extensive tissue death occurs.
Outlook (Prognosis) Return to top
Symptoms of thromboangiitis obliterans may disappear if the person stops tobacco use. For some, amputation is unavoidable.
Possible Complications Return to top
When to Contact a Medical Professional Return to top
Call your health care provider if you have symptoms of thromboangiitis obliterans, if you have thromboangiitis obliterans and symptoms get worse despite treatment, or if new symptoms develop.
Prevention Return to top
Those with a history of Raynaud's disease or thromboangiitis obliterans should avoid all tobacco use.
References Return to top
Olin JW. Other peripheral arterial diseases. In: Goldman L, Ausiello D, eds. Cecil Medicine. 23rd ed. Philadelphia, Pa: Saunders Elsevier; 2007: chap 80.Update Date: 10/27/2008 Updated by: Neil J. Gonter, MD, Assistant Professor of Medicine, Columbia University, New York, NY, and private practice specializing in Rheumatology at Rheumatology Associates of North Jersey, Teaneck, NJ. Review provided by Verimed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.