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Temporal lobe seizure

Contents of this page:


Central nervous system
Central nervous system

Alternative Names    Return to top

TLE; Seizure - temporal lobe

Definition    Return to top

This type of seizure arises from abnormal electrical activity in the temporal lobe on one or both sides of the brain.

Causes    Return to top

A seizure is an episode of abnormal electrical activity in the brain that can cause loss of, or reduced, consciousness; involuntary movements; and unusual sensations. When the electrical activity starts in the temporal lobe, it produces a temporal lobe seizure.

Temporal lobe seizures can affect people of any age, and can occur as a single episode or can be repeated as part of a chronic (ongoing) condition. (See seizure disorder/epilepsy).

Brain cells communicate with each other and produce our consciousness, thoughts, and actions by electrochemical processes. Certain patterns of electrical activity disrupt this normal function of the brain and spread in abnormal patterns within the brain. This process can be seen on a brainwave test, called an electroencephalograph (EEG).

Under the right conditions, such as exposure to certain drugs, high fever, or electrical stimulation, anyone can have a seizure. The temporal lobe of the brain is one area that is particularly likely to have a seizure.

Temporal lobe seizures commonly result from damage to specific areas in that part of the brain. This can be due to a head injury, infection, or damage to a portion of the temporal lobe due to lack of oxygen, brain tumors, genetic syndromes, or lesions of any sort. Many of these problems also produce brain-tissue scarring called mesial temporal sclerosis.

Because the temporal lobe is involved in consolidating memories and processing emotions, seizures in this area may begin with feelings of fear, feelings of joy (sometimes with religious associations and the sensation of a "presence"), recall of certain music, or smells and other unusual symptoms.

Symptoms    Return to top

The early warning symptoms (called an aura) of a seizure are caused by the beginning of the seizure in a small part of the temporal lobe. The aura may stop on its own, or go on to spread, producing altered awareness. The aura, also called a "simple partial seizure," can include:

If the electrical activity spreads and consciousness is altered or memory is lost, the seizure is called "complex partial." During this part of the seizure, the following may occur:

Exams and Tests    Return to top

Temporal lobe seizures may be suspected based on the person's symptoms and the results of tests. Diagnosis may include a complete physical examination, including a detailed neuromuscular examination, which may or may not be normal.

Treatment    Return to top

The goals of treatment are to perform emergency measures, if necessary, and to reduce the rate of future seizures.

Emergency treatment may not be required, unless the seizure becomes generalized or movement and behavior puts the person in danger. First-aid measures should be done as appropriate, including protecting the person from injury, preventing the person from breathing vomit or mucus into their lungs, and protecting their airway or assisting them with breathing.

Important details that should be recorded and reported to the person's doctor include date and time of the seizure, how long it lasted, which body parts were involved, the type of movements or other symptoms, possible causes, and other factors that provide information about the episode (such as what happened immediately before the seizure began).

Treating certain causes may stop the seizures. This may include medical treatment of seizure disorders like epilepsy, surgical removal of tumors or brain lesions, and other treatments as needed.

Oral anticonvulsants (anti-seizure medications taken by mouth) are used to prevent or reduce the number of future seizures. How well these drugs work depends on the individual, and the medication and the dosage may have to be adjusted repeatedly.

Multiple, repeated seizures are usually treated with long-term use of an antiepileptic drug.

Follow-up includes reviewing the need for drugs at least yearly. The person may need to remain on the drugs for their entire life. Monitoring the level of medicine in the blood is important to continue control of seizures, and to reduce side effects.

Pregnancy, lack of sleep, skipping doses of medications, use of recreational drugs (including alcohol), or illness may cause seizures in a person with a previously well-controlled seizure disorder.

The person may be advised to wear or carry informational jewelry or cards (such as Medic-Alert or similar) that indicate they have a seizure disorder. These accessories may help in getting quick medical treatment if a seizure happens.

Outlook (Prognosis)    Return to top

A seizures can happen as a single, one-time event or can happen over and over with no clear reason. When seizures happen over and over with no obvious cause, it is referred to as epilepsy.

Seizures that occur once or in a single cluster are commonly caused by a recent problem such as a brain injury. They may be due to a single, isolated problem that won't happen again, but the seizures can develop into epilepsy. Seizures within the first 2 weeks of a brain injury do NOT necessarily mean that epilepsy will develop.

Serious injury can occur if a seizure happens while driving, or when operating dangerous equipment. Each state has different policies on driving restrictions. Swimming and bathing without supervision can also be dangerous, as can contact sports. Your doctor may suggest that you stop these activities if you have poorly controlled seizures.

Possible Complications    Return to top

When to Contact a Medical Professional    Return to top

Go to the emergency room or call 911 if:

Prevention    Return to top

Treatment of any lesions or disorders may reduce the seizures. In many cases, epilepsy is caused by a genetic disorder and may not be preventable.

References    Return to top

Foldvary-Schaefer N, Wyllie E. Epilepsy. In: Goetz, CG, ed. Textbook of Clinical Neurology. 3rd ed. Philadelphia, PA: Saunders Elsevier; 2007: chap 52.

Krumholz A, Wiebe S, Gronseth G, et al. Practice Parameter: evaluating an apparent unprovoked first seizure in adults (an evidence-based review): report of the Quality Standards Subcommittee of the American Academy of Neurology and the American Epilepsy Society. Neurology. 2007;69(21):1996-2007.

Pollack CV, Jr. Seizures. In: Marx, JA, ed. Rosen's Emergency Medicine: Concepts and Clinical Practice. 6th ed. Philadelphia, PA: Mosby Elsevier; 2006: chap 100.

Spencer SS. Seizures and Epilepsy. In: Goldman L, Ausiello D, eds. Cecil Medicine. 23rd ed. Philadelphia, PA: Saunders Elsevier; 2007: chap 426.

Update Date: 6/11/2008

Updated by: Daniel B. Hoch, PhD, MD, Assistant Professor of Neurology, Harvard Medical School, Department of Neurology, Massachusetts General Hospital. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.

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