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Cold knife cone biopsy

Contents of this page:


Female reproductive anatomy
Female reproductive anatomy
Cold cone biopsy
Cold cone biopsy
Cold cone removal
Cold cone removal

Alternative Names    Return to top

Cone biopsy; Biopsy - cone; Cervical conization

Definition    Return to top

A cold knife cone biopsy is a procedure to get a sample of abnormal tissue from the cervix for further examination.

See also:

How the Test is Performed    Return to top

This is a surgical procedure. It is done in the hospital while you are either sedated through an IV or general anesthesia. The purpose of this procedure is to diagnose and treat precancerous changes in the cervix.

A small cone-shaped sample of tissue is removed from the cervix and examined under a microscope for any signs of cancer. This biopsy may also be the treatment if the doctor removes all of the diseased tissue.

How to Prepare for the Test    Return to top

As with any procedure that is done under anesthesia, you will probably need to fast for 6 - 8 hours. You must sign an informed consent form. The procedure is done on the same day (outpatient) and a hospital stay is usually not needed.

How the Test Will Feel    Return to top

After the procedure, you may have some cramping or discomfort for a week or so. For about 4 - 6 weeks avoid:

For 2 - 3 weeks after the procedure, you may have discharge that is:

Why the Test is Performed    Return to top

This test is only done if the health care provider knows or suspects that you have abnormal cells in the cervix.

It may be done if a biopsy of the cervix shows that you may have precancerous cells in the area or cervical cancer. A cold knife biopsy may also be done if a cervical biopsy cannot find the cause of an abnormal Pap smear.

Normal Results    Return to top

There are no precancerous or cancerous cells in the cervix.

What Abnormal Results Mean    Return to top

Most often, abnormal results mean that there is an area of precancerous or cancerous cells.

Risks    Return to top

References    Return to top

Katz VL, Lentz GM, Lobo RA, Gershenson DM. Comprehensive Gynecology. Philadelphia, Pa: Mosby; 2007.

Update Date: 2/19/2008

Updated by: Peter Chen, MD, Department of Obstetrics & Gynecology, University of Pennsylvania Medical Center, Philadelphia, PA. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.

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